Skip to main content
Figure 3 | BMC Cancer

Figure 3

From: Therapeutic potential of cladribine in combination with STAT3 inhibitor against multiple myeloma

Figure 3

Cladribine induces apoptosis in MM cells. A, U266 cells were cultured with RPMI1640 (0.5% FBS) in the absence or presence of indicated concentrations of cladribine for 24 hrs. Cells were harvested and double-stained with Annexin V/PI, and then subjected to FACScan. The percentages of Annexin V-positive staining cells, indicative of apoptosis, were shown. B & C, RPMI8226 and MM1.S cells were cultured with RPMI1640 (0.5% FBS) in the absence or presence of indicated concentrations of cladribine for 24 hrs. Cells were collected and subjected to a specific apoptotic-ELISA. Bars, SD.

Back to article page