NDRG2 inhibits hepatocellular carcinoma adhesion, migration and invasion by regulating CD24 expression

BMC Cancer

Table 1 Correlation of NDRG2 expression with HCC clinical features in 50 primary HCC specimens

Features*		NDRG2 expression Negative/weak (%)	P
Age(years)
≤50	n = 21	18(85.7)	0.616
> 50	n = 29	22(75.9)
Sex
Male	n = 34	15(44.1)	0.981
Female	n = 16	7(43.8)
Tumor size
≤5 cm	n = 39	23(59.0)	0.184
>5 cm	n = 11	4(36.4)
CD24
Positive	n = 29	22(75.9)	0.040
Negative/weak	n = 21	10(47.6)
Serum AFP level(ng/ml)
≥ 320	n = 32	25(78.1)	0.006
< 320	n = 18	7(38.9)
TNM stage
I-II	n = 27	10(37.0)	0.009
III-IV	n = 23	17(73.9)
Edmondson
I-II	n = 24	7(29.2)	0.002
III-IV	n = 26	19(73.1)
Tumor invasion
+	n = 32	24(75.0)	0.004
-	n = 18	6(33.3)
Tumor recurrence
+	n = 33	27(81.8)	0.024
-	n = 12	5(41.7)

* +, positive; -, negative; n, number of cases; grades I-II, well-differentiated HCC; grades III-IV, poorly differentiated HCC.

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