Figure 3

Overexpression of NDRG2 suppresses the adhesion, migration and invasion of MHCC97H cells. NDRG2-low HCC MHCC97H cells were infected with adenovirus expressing NDRG2 (Ad-NDRG2) or the negative control gene Lac Z (Ad-LacZ). The cells were subjected to adhesion (A and B), migration (C and D) and invasion assays (E and F), respectively. In (B), (D) and (F), the histograms represent the quantification of cells attached, wounding remaining width and cells having invaded through Matrigel. Data represent three independent experiments. *P < 0.05 between groups.