Cell-dependent motility phenotypes were observed in FAP
+ matrix. To determine ECM effects on the invasive behaviors of cancer cells, time-lapse acquisition assays were performed on FAP+ matrices using pancreatic cancer cell lines. Representative tracks are shown where each cell line presented distinct responses to the FAP+ matrix as measured by average velocity (μm/hr) and directionality (D/T). Statistical significances were marked using asterisks.