|
Matrix metallopeptidase 7
|
↑
|
110
|
Breakdown of extracellular matrix, metastasis
|
MMP7 (4316)
|
|
Keratin 23
|
↑
|
77
|
Structural integrity of epithelial cells
|
KRT23 (25984)
|
|
Myosin
|
↑
|
63
|
Muscle, heavy polypeptide 2
|
MYH2 (4620)
|
|
Claudin 1
|
↑
|
38
|
Integral membrane protein, component of tight junction strands
|
CLDN1 (9076)
|
|
Actin α1, skeletal
|
↑
|
36
|
Cell motility, structure and integrity
|
ACTA1 (58)
|
|
Forkhead box Q1
|
↑
|
34
|
Transcription factor (i.e. TGF-beta2)
|
FOXQ1 (94234)
|
|
Proprotein convertase subtilisin/kexin type 1
|
↑
|
22
|
Regulating insulin biosynthesis, obesity, activate precursor protein, associated with carcinoid tumors
|
PCSK1 (5122)
|
|
Sarcolipin
|
↑
|
25
|
Regulates several sarcoplasmic reticulum Ca(2+)-ATPases
|
SLN (6588)
|
|
Matrix metallopeptidase 1
|
↑
|
14
|
Breakdown of extracellular matrix, metastasis
|
MMP1 (4312)
|
|
Myosin, cardiac, beta
|
↑
|
25
|
Heavy chain, also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers
|
MYH7 (4625)
|
|
Hydroxy-δ-5-steroid dehydrogenase
|
↓
|
79
|
Biosynthesis of steroid hormones, polymorphisms related to prostate cancer
|
HSD3B2 (3284)
|
|
Hydroxy-δ-5-steroid dehydrogenase
|
↓
|
30
|
Biosynthesis of steroid hormones, diagnostic trophoblastic marker
|
HSD3B1 (3283)
|
|
similar to 3 β-hydroxysteroid dehydrogenase
|
↓
|
28
|
Pseudogene
|
LOC391081 (391081)
|
|
-
|
↓
|
24
|
unknown
|
CR627415
|
|
Butyrylcholinesterase
|
↓
|
21
|
Homozygoutics sustain prolonged apnea after administration of the muscle relaxant suxamethonium
|
BCHE (590)
|
|
Neuronal pentraxin
|
↓
|
19
|
Excitatory synapse remodelling, mediate neuronal death induced by reduction in neuronal activity in mature neurons
|
NPTX1 (4884)
|
|
Dipeptidyl-peptidase 6
|
↓
|
18
|
Binds and alters specific voltage-gated potassium channels expression and biophysical properties
|
DPP6 (1804)
|
|
ATP-binding cassette, sub-family G
|
↓
|
17
|
Breast cancer resistance protein, xenobiotic transporter may play a major role in multi-drug resistance
|
ABCG2 (9429)
|
|
Insulin like-5
|
↓
|
17
|
Relaxin/Insulin family, ligand for GPCR142
|
INSL5 (10022)
|
|
Regenerating islet-derived 1 β
|
↓
|
16
|
Highly similar to REG1A protein (islet cell regeneration and diabetogenesis)
|
REG1B (5968)
|
