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Table 3 Summary of pulmonary lesions in treatment groups

From: Bicarbonate and dichloroacetate: Evaluating pH altering therapies in a mouse model for metastatic breast cancer

  Untreated Bicarbonate DCA DB
Lungs analyzed per group 10 1 6 9
Total number of lesions 77 32 71 122
Metastases area sum (lesion pixels) 56090 39289 47428 26897
Metastases area mean (lesion pixels ± SEM) 728 ± 105 1228 ± 220* 668 ± 77 220 ± 18**
Metastases area median (lesion pixels) 447 720 419 160
  1. Metastases lesion areas were determined by measurement of the two-dimensional pixel area. Two diseased lungs, one from the untreated group and one from the DB treated group, could not be reliably measured to include in the analysis. A single asterisk (*) designates lesion areas that were significantly different from pulmonary lesions in untreated mice (p < 0.05). A double asterisk (**) designates lesion areas that were significantly different from pulmonary lesions in untreated mice (p < 0.001).