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Table 3 Summary of pulmonary lesions in treatment groups

From: Bicarbonate and dichloroacetate: Evaluating pH altering therapies in a mouse model for metastatic breast cancer

 

Untreated

Bicarbonate

DCA

DB

Lungs analyzed per group

10

1

6

9

Total number of lesions

77

32

71

122

Metastases area sum (lesion pixels)

56090

39289

47428

26897

Metastases area mean (lesion pixels ± SEM)

728 ± 105

1228 ± 220*

668 ± 77

220 ± 18**

Metastases area median (lesion pixels)

447

720

419

160

  1. Metastases lesion areas were determined by measurement of the two-dimensional pixel area. Two diseased lungs, one from the untreated group and one from the DB treated group, could not be reliably measured to include in the analysis. A single asterisk (*) designates lesion areas that were significantly different from pulmonary lesions in untreated mice (p < 0.05). A double asterisk (**) designates lesion areas that were significantly different from pulmonary lesions in untreated mice (p < 0.001).