|
Untreated
|
Bicarbonate
|
DCA
|
DB
|
---|
Lungs analyzed per group
|
10
|
1
|
6
|
9
|
Total number of lesions
|
77
|
32
|
71
|
122
|
Metastases area sum (lesion pixels)
|
56090
|
39289
|
47428
|
26897
|
Metastases area mean (lesion pixels ± SEM)
|
728 ± 105
|
1228 ± 220*
|
668 ± 77
|
220 ± 18**
|
Metastases area median (lesion pixels)
|
447
|
720
|
419
|
160
|
- Metastases lesion areas were determined by measurement of the two-dimensional pixel area. Two diseased lungs, one from the untreated group and one from the DB treated group, could not be reliably measured to include in the analysis. A single asterisk (*) designates lesion areas that were significantly different from pulmonary lesions in untreated mice (p < 0.05). A double asterisk (**) designates lesion areas that were significantly different from pulmonary lesions in untreated mice (p < 0.001).