Figure 5From: In vitro anti-angiogenic properties of LGD1069, a selective retinoid X-receptor agonist through down-regulating Runx2 expression on Human endothelial cells Effects of LGD1069 on metalloproteinases activities in HUVECs. HUVECs were incubated for 12 h in medium containing vehicle (DMSO, Line 1) or 7.5 μM, 15 μM, and 30 μM LGD1069, in the presence of 2 ng/ml VEGF. Data were expressed as mean ± S.D. a p < 0.05, b p < 0.01 compared with control.Back to article page