Table 2 Type of Acute Leukemia, Initial Symptoms, Hematology and Degree of Bone Marrow Cellularity
Total | Type of Acute Leukemia-ALL | Type of Acute Leukemia-AML | |||||||
|---|---|---|---|---|---|---|---|---|---|
Initial symptom | Younger Group (n = 183) | Elderly Group (n = 183) | p-value1 | Younger Group (n = 67) | Elderly Group (n = 19) | p-value1 | Younger Group (n = 116) | Elderly Group (n = 164) | p-value1 |
Hypodynamia | 106 (57.9) | 123 (67.2) | 0.066 | 39 (58.2) | 11 (57.9) | 0.980 | 67 (57.8) | 112 (68.3) | 0.071 |
Pale face | 109 (59.6) | 97 (53.0) | 0.206 | 39 (58.2) | 6 (31.6) | 0.040* | 70 (60.3) | 91 (55.5) | 0.418 |
Fever | 78 (42.6) | 61 (33.3) | 0.067 | 31 (46.3) | 6 (31.6) | 0.254 | 47 (40.5) | 55 (33.5) | 0.232 |
Hemorrhagic dermatologic mucosa | 25 (13.7) | 25 (13.7) | 1.000 | 7 (10.4) | 2 (10.5) | 1.000 | 18 (15.5) | 23 (14.0) | 0.728 |
Dizziness | 29 (15.8) | 20 (10.9) | 0.167 | 12 (17.9) | 3 (15.8) | 1.000 | 17 (14.7) | 17 (10.4) | 0.279 |
WBC infiltration** | 17 (9.3) | 24 (13.1) | 0.246 | 9 (13.4) | 4 (21.1) | 0.471 | 8 (6.9) | 20 (12.2) | 0.145 |
Lower extremity edema | 0(0) | 5(2.73) | 0.024 | 0 (0) | 2 (10.5) | 0.047* | 0 (0) | 3 (1.8) | 0.269 |
Myalgias | 5(2.73) | 5(2.73) | 1.000 | 0 (0) | 0 (0) | - | 5 (4.3) | 5 (3.0) | 0.575 |
White cell count (109/L) | 0.139 | 0.057 | 0.012* | ||||||
<4 | 56 (30.6) | 69 (37.7) | 28 (41.8) | 3 (15.8) | 28 (24.1) | 66 (40.2) | |||
4 - 10 | 29 (15.8) | 18 (9.8) | 10 (14.9) | 2 (10.5) | 19 (16.4) | 16 (9.8) | |||
>10 | 98 (53.6) | 96 (52.5) | 29 (43.3) | 14 (73.7) | 69 (59.5) | 82 (50.0) | |||
Hemoglobin (g/L)2 | 0.549 | 0.078 | 0.336 | ||||||
Abnormal | 168 (91.8) | 171 (93.4) | 60 (89.6) | 14 (73.7) | 108 (93.1) | 157 (95.7) | |||
Normal | 15 (8.2) | 12 (6.6) | 7 (10.4) | 5 (26.3) | 8 (6.9) | 7 (4.3) | |||
Platelets (109/L) | 0.018* | 0.273 | 0.127 | ||||||
≦ 10 | 59 (32.2) | 39 (21.3) | 25 (37.3) | 4 (21.1) | 34 (29.3) | 35 (21.3) | |||
>10 | 124 (67.8) | 144 (78.7) | 42 (62.7) | 15 (78.9) | 82 (70.7) | 129 (78.7) | |||
Bone marrow cellularity | 0.014* | 0.400 | 0.002* | ||||||
Severely hypercellular | 90 (49.2) | 61 (33.3) | 28 (41.8) | 11 (57.9) | 62 (53.4) | 50 (30.5) | |||
Moderately hypercellular | 38 (20.8) | 58 (31.7) | 13 (19.4) | 1 (5.3) | 25 (21.6) | 57 (34.8) | |||
Normocellular | 31 (13.1) | 39 (21.3) | 15 (22.4) | 5 (26.3) | 16 (13.8) | 34 (20.7) | |||
Hypocellular | 24 (13.1) | 25 (13.7) | 11 (16.4) | 2 (10.5) | 13 (11.2) | 23 (14.0) | |||