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Table 1 Patient Characteristics

From: Clinical symptoms and chemotherapy completion in elderly patients with newly diagnosed acute leukemia: a retrospective comparison study with a younger cohort

 

Total

Type of Leukemia-ALL2

Type of Leukemia-AML2

 

Younger

Group

(n = 183)

Elderly

Group

(n = 183)

p-value1

Younger

Group

(n = 67)

Elderly

Group

(n = 19)

p-value1

Younger

Group

(n = 116)

Elderly

Group

(n = 164)

p-value1

Age (years)

34.4 ± 13.1

70.1 ± 6.4

<0.001*

30.2 ± 13.3

69.3 ± 5.5

<0.001*

36.8 ± 12.4

70.2 ± 6.5

<0.001*

Male gender

111 (60.7)

116 (63.4)

0.59

46 (68.7)

10 (52.6)

0.196

65 (56.0)

106 (64.6)

0.146

Married

131 (71.6)

183 (100.0)

<0.001*

34(50.7)

19 (100)

<0.001*

97 (83.6)

164 (100)

<0.001*

Smoking

14 (7.7)

34 (18.6)

0.002*

3 (4.5)

3 (15.8)

0.122

11 (9.6)

31 (18.9)

0.032*

Alcohol use**

4 (2.2)

12 (6.6)

0.041*

1 (1.5)

0 (0)

1.000

3 (2.6)

12 (7.3)

1.000

History of carcinoma***

4 (2.2)

4 (2.2)

1.000

0 (0)

1 (5.3)

0.221

4 (3.4)

3 (1.8)

0.454

Lung infection

18 (9.8)

47 (25.7)

<0.001*

3 (4.5)

3 (15.8)

0.119

15 (12.9)

44 (26.8)

0.005*

Cardiovascular disease

0 (0.0)

8 (4.4)

0.007*

0 (0)

0 (0)

-

0 (0)

8 (4.9)

0.023*

Hypertension

3 (1.6)

38 (20.8)

<0.001*

2 (3.0)

5 (26.3)

0.005*

1 (0.9)

33 (20.1)

<0.001*

Diabetes

4 (2.2)

14 (7.7)

0.016*

0 (0)

2 (10.5)

0.047*

4 (3.4)

12 (7.3)

0.200

COPD

0 (0.0)

9 (4.9)

0.004*

0 (0)

0 (0)

-

0 (0)

9 (5.5)

0.012*

Hepatitis B

14 (7.7)

8 (4.4)

0.187

9 (13.4)

3 (15.8)

0.723

5 (4.3)

5 (3.0)

0.575

  1. Data were represented as n (%) except age was as mean ± SD
  2. SD = standard deviation; COPD = chronic obstructive pulmonary disease
  3. 1 Chi-square test or Fishers' exact test was used for categorical data and independent t-test was used for age.
  4. 2 The types were based on French-American-British classification.
  5. *Indicates significant differences between two groups, p < 0.05.
  6. **Consuming 5 or more drinks per day.
  7. ***History of other malignant tumors occurring before the diagnosis of acute leukemia.