Synergistic effects of oncolytic reovirus and docetaxel chemotherapy in prostate cancer

BMC Cancer

Table 2 Interaction of reovirus and chemotherapy on Du 145^a

Chemotherapeutic	ED50	ED75	ED90
Docetaxel	1.02 ± 0.05	0.83 ± 0.03	0.75 ± 0.07
Paclitaxel	0.89 ± 0.06	0.70 ± 0.08	0.58 ± 0.10
Vincristine	0.80 ± 0.01	0.57 ± 0.05	0.44 ± 0.08
Cisplatin	0.74 ± 0.13	0.61 ± 0.06	0.52 ± 0.06
Doxorubicin	0.82 ± 0.03	0.69 ± 0.03	0.59 ± 0.06

^adata is presented as combination index values ± SEM of three independent experiments at the effective dose indicated

ISSN: 1471-2407