Synergistic effects of oncolytic reovirus and docetaxel chemotherapy in prostate cancer

BMC Cancer

Table 1 Interaction of reovirus and chemotherapy on PC3^a

Chemotherapeutic	ED50	ED75	ED90
Docetaxel	0.41 ± 0.07	0.75 ± 0.04	1.58 ± 0.08
Paclitaxel	0.57 ± 0.01	0.40 ± 0.03	0.31 ± 0.04
Vincristine	0.46 ± 0.06	0.34 ± 0.05	0.44 ± 0.11
Cisplatin	0.89 ± 0.06	0.51 ± 0.07	0.33 ± 0.05
Doxorubicin	0.49 ± 0.03	0.22 ± 0.03	0.11 ± 0.03

^adata is presented as combination index values ± SEM of three independent experiments at the effective dose indicated

ISSN: 1471-2407