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Table 2 Association of E-cadherin with tumour stage, differentiation grade and lymph node status

From: Down regulation of E-Cadherin (ECAD) - a predictor for occult metastatic disease in sentinel node biopsy of early squamous cell carcinomas of the oral cavity and oropharynx

 

Cadherin low (IRS ≤ 9)

n = 79 (65.8%)

Cadherin high (IRS > 9)

n = 41 (34.2%)

P -value

Tumor stage

  

0.4451)

   pT1

40 (50.6%)

24 (58.5%)

 

   pT2

39 (49.4%)

17 (41.5%)

 

Differentiation grade*

  

0.0182)

   Grade I (well)

7 (9.5%)

7 (18.4%)

 

   Grade II (moderate)

51 (68.9%)

29 (76.3%)

 

   Grade III (poor)

16 (21.6%)

2 (5.3%)

 

Sentinel node

  

0.0051)

   negative

42 (53.2%)

33 (80.5%)

 

   positive

37 (46.8%)

8 (19.5%)

 
  1. *Eight patients with differentiation grade not otherwise specified have been excluded
  2. 1) Fisher's exact test, 2) exact Mann-Whithey U test
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BMC Cancer

ISSN: 1471-2407

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