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Table 2 Summary of univariate analysis

From: Prognostic value of the expression of C-Chemokine Receptor 6 and 7 and their ligands in non-metastatic breast cancer

Characteristics

N

Mean RFS (years)

95% CI

p value for LR

Mean OS (years)

95% CI

p value for LR

Age (range)

       

< 40 years

15

8.1

6.3-10.0

 

10.6

10.1-11.1

 

40-55 years

82

11.1

10.5-11.7

 

11.2

10.7-11.8

 

> 55 years

110

10.3

9.6-11.1

0.084

10.2

9.5-10.9

0.051

Tumor size

       

T1

121

11.1

10.6-11.7

 

11.1

10.6-11.7

 

T2

76

10.0

9.1-10.8

 

10.5

9.9-11.2

 

T3-T4

10

6.1

2.9-9.4

< 0.001

6.6

3.6-9.6

< 0.001

Lymph node

       

Negative

106

11.0

10.5-11.7

 

11.2

10.7-11.7

 

Positive

101

10.0

9.2-10.7

0.031

10.1

9.4-10.8

0.030

Histology

       

Ductal

173

10.6

10.0-11.1

 

10.6

10.1-11.1

 

Lobular

24

10.5

9.1-11.9

 

11.5

10.8-12.3

 

Other

10

9.8

7.4-12.3

0.722

10.4

7.8-12.9

0.410

Tumor grade (Scarff-Bloom-Richardson)

       

I

52

11.9

11.4-14.4

 

11.7

11.1-12.3

 

II

96

10.4

9.6-11.1

 

10.6

10.0-11.2

 

III

59

9.4

8.2-11.1

0.003

9.9

8.9-10.9

0.024

Estrogen receptor

       

Negative

53

9.6

8.4-10.7

 

10.2

9.2-11.2

 

Positive

153

11.0

10.5-11.5

0.012

11.0

10.5-11.5

0.354

Progesterone receptor

       

Negative

61

9.5

8.4-10.6

 

9.9

9.0-10.9

 

Positive

145

11.1

10.6-11.6

0.013

11.2

10.7-11.6

0.035

Her2-neu expression (IHC)

       

0, 1+ or 2+

182

10.6

10.1-11.1

 

10.7

10.3-11.2

 

3+

22

9.7

8.4-10.9

0.819

10.1

9.2-11.0

0.886

CCR6 on tumor cells

       

Negative

130

11.0

10.4-11.6

 

10.9

10.3-11.4

 

Positive

72

9.9

9.0-10.8

0.032

10.5

9.8-11.2

0.400

CCR7 on stromal cells

       

Negative

118

10.8

10.2-11.5

 

11.0

10.5-11.6

 

Positive

89

10.3

9.4-11.1

0.344

10.4

9.6-11.1

0.153

CCL19 on tumor cells

       

Negative

95

10.4

9.6-11.2

 

10.7

10.0-11.3

 

Positive

109

10.7

10.0-11.4

0.730

10.8

10.2-11.4

0.962

CCL19 on dendritic cells

       

Negative

103

11.0

10.4-11.7

 

11.0

10.3-11.5

 

Positive

101

9.8

9.1-10.6

0.042

10.2

9.6-10.9

0.271

  1. IHC: assessed by immunohistochemistry.