Figure 1From: MDM2 antagonist Nutlin-3a potentiates antitumour activity of cytotoxic drugs in sarcoma cell lines Representative growth inhibition curves for OSA (A) and RMS13 (B) after Nutlin-3a, Doxorubicin, Cisplatin and Methotrexate exposures. Exponentially growing cancer cells with TP53 Wt(OSA) or TP53 Mut(RMS13) were incubated with a range of drug concentrations for 120 h. Relative growth was measured by the SRB assay.Back to article page