Skip to main content

Table 1 Concentration of MF needed to achieve 50% growth inhibition (IC50) of the cell lines studied and their doubling times (DT)

From: Antiprogestin mifepristone inhibits the growth of cancer cells of reproductive and non-reproductive origin regardless of progesterone receptor expression

Origin Cell Line IC50 (μM) DT (h)
N. System IOMM-Lee 9.4 ± 1.2 13.9
N. System U87MG 23.2 ± 0.0 36.9
Breast MCF-7 17.7 ± 2.0 37.7
Breast MDA-MB-231 29.2 ± 1.3 33.3
Prostate LNCaP 14.1 ± 0.5 50.7
Prostate PC-3 18.5 ± 2.0 30.7
Ovary OVCAR-3 19.0 ± 1.3 55.7
Ovary SK-OV-3 12.6 ± 0.1* 36.9
Bone U-2OS 21.9 ± 2.3 29.2
Bone SAOS-2 18.7 ± 3.2 49.2
  1. IC50 data are expressed as mean ± s.e.m of three experiments each one performed in triplicate. DT data are the result of one experiment performed in triplicate (see Additional file 1: Figure S1). *Date obtained from our previously published work [14]
Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us