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Figure 8 | BMC Cancer

Figure 8

From: Variations in Mre11/Rad50/Nbs1 status and DNA damage-induced S-phase arrest in the cell lines of the NCI60 panel

Figure 8

Correlation of sensitivity to representative benzothiazoles and lack of SN38-mediated S-phase arrest. The mean graphs for sensitivity to NSC 696154 (left panel, red lines) or NSC 702154 (right panel, red lines) are compared to the concentration of SN38 which causes S-phase arrest in each cell line (open bars). The observation that the red lines and boxes have a direct correlation reflect the fact that drug sensitivity correlates with a deficiency in S phase arrest.

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