Accession No. | Gene Symbol | Gene Name | Melan. | IgR3 | Mel-RM |
---|---|---|---|---|---|
Genes regulated similarly by p53 KO in melanocytes and melanoma cells | Â | Â | Â | ||
Cell cycle, proliferation or differentiation | Â | Â | Â | ||
NM_000389.2 | CDKN1A | Cyclin-dependent kinase inhibitor 1A, transcript variant 1 | 2.68 | - | 7.12 |
NM_004864.1 | GDF15 | Growth differentiation factor 15 | 3.42 | - | 6.11 |
Transcription regulation/signal transduction | Â | Â | Â | ||
NM_014376.2 | CYFIP2 | Cytoplasmic FMR1 interacting protein 2, transcript variant 3 | 5.11 | - | 8.88 |
Genes regulated by p53 KO in melanoma cells but not in melanocytes | Â | Â | Â | ||
Apoptosis | Â | Â | Â | Â | Â |
NM_138578.1 | BCL2L11 | BCL2-like 1 (Bcl-xL), transcript variant 1 | - | -2.06 | 2.01 |
NM_033294.2 | CASP1 | Caspase 1, transcript variant delta | - | - | -4.20 |
NM_016479.3 | SHISA5 | Shisa homolog 5 | - | -2.30 | - |
NM_019058.2 | DDIT4 | DNA-damage-inducible transcript 4 | - | -2.56 | - |
Cell cycle, proliferation or differentiation | Â | Â | Â | ||
NM_078467.1 | CDKN1A | Cyclin-dependent kinase inhibitor 1A, transcript variant 2 | - | - | 7.56 |
NM_000548.3 | TSC2 | Tuberous sclerosis 2, transcript variant 1 | - | - | 3.95 |
Immunity and defense | Â | Â | Â | Â | |
NM_003897.3 | IER3 | Immediate early response 3 | - | - | 2.59 |
Metabolism | Â | Â | Â | Â | Â |
NM_000603.3 | NOS3 | Nitric oxide synthase 3 | -2.72 | 10.65 | - |
Transcription regulation/signal transduction | Â | Â | Â | ||
NM_001037333.1 | CYFIP2 | Cytoplasmic FMR1 interacting protein 2, transcript variant 1 | - | - | 14.63 |
NM_152546.1 | SRFBP1 | Serum response factor binding protein 1 | - | - | -2.12 |
NM_004559.3 | YBX1 | Y box binding protein 1 | - | -2.75 | - |
Transport | Â | Â | Â | Â | Â |
NM_000593.5 | TAP1 | Transporter 1 | - | 2.07 | - |
Unknown function | Â | Â | Â | Â | Â |
NM_182915.2 | STEAP3 | STEAP family member 3, transcript variant 1 | - | 4.64 | -2.94 |
Genes regulated by p53 KO in melanocytes but not in melanoma | Â | Â | Â | ||
Apoptosis | Â | Â | Â | Â | Â |
NM_001040619.1 | ATF3 | Activating transcription factor 3, transcript variant 4 | -5.30 | - | - |
NM_001008925.1 | RCHY1 | Ring finger and CHY zinc finger domain containing 1, transcript variant 2 | -12.23 | - | - |
NM_005427.1 | TP73 | Tumor protein p73 | 10.54 | - | 2.84 |
Cell cycle, proliferation or differentiation | Â | Â | Â | ||
NM_001012271.1 | BIRC51 | Baculoviral IAP repeat-containing 5, transcript variant 3 | -18.95 | - | - |
NM_004701.2 | CCNB2 | Cyclin B2 | -3.17 | - | - |
NM_057735.1 | CCNE21 | Cyclin E2, transcript variant 2 | -5.73 | - | - |
NM_001786.2 | CDC21 | Cell division cycle 2, transcript variant 1 | -8.42 | - | - |
NM_022809.2 | CDC25C1 | Cell division cycle 25 homolog C, transcript variant 2 | -9.40 | - | - |
NM_001259.5 | CDK6 | Cyclin-dependent kinase 6 | 2.15 | - | - |
NM_058195.2 | CDKN2A1 | Cyclin-dependent kinase inhibitor 2A, transcript variant 4 | -12.78 | - | - |
NM_006622.2 | PLK2 | Polo-like kinase 2 | 18.00 | -8.19 | - |
NM_014454.1 | SESN1 | Sestrin 1 | 2.69 | - | - |
Immunity and defense | Â | Â | Â | Â | |
NM_003246.2 | THBS1 | Thrombospondin 1 | -18.25 | - | - |
NM_003247.2 | THBS2 | Thrombospondin 2 | 2.21 | - | - |
NM_033550.3 | TP53RK | TP53 regulating kinase | -2.08 | - | - |
Transcription regulation/signal transduction | Â | Â | Â | ||
NM_000376.2 | VDR | Vitamin D receptor, transcript variant 1 | -20.88 | - | - |