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Table 1 Summary of the overall DNA copy number status in the study population.

From: Molecular cytogenetic characterization of canine histiocytic sarcoma: A spontaneous model for human histiocytic cancer identifies deletion of tumor suppressor genes and highlights influence of genetic background on tumor behavior

 

BMD

FCR

Mean (+/- st.dev)

mean number of CNAs

30.3 ± 17.8

32.2 ± 17.8

30.7 ± 17.6

mean number of losses

15.9 ± 9.3

18.1 ± 7.2

16.7 ± 8.6

mean number of gains

13.8 ± 10.3

14.1 ± 12.3

13.9 ± 10.9

ratio losses:gains

1.15:1

1.27:1

1.22:1

mean size of loss (Mb)

30.7 ± 21

35.7 ± 20.5

32.5 ± 21

mean size of gain (Mb)

23.3 ± 23.7

22.4 ± 20.5

23.1 ± 22.6

  1. (CNAs = Copy Number Aberrations, BMD = Bernese Mountain Dog, FCR = Flat Coated Retriever, Mb = Megabase).
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BMC Cancer

ISSN: 1471-2407

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