Table 2 Distribution of EORTC QLQ-C30 domain and symptom item scales by site

Global Score ^a

50.78 ± 3.15

49.80 ± 4.84

51.96 ± 3.86

-

54.7 (23.8)

Functional Scales ^a

Physical

64.53 ± 3.15

73.33 ± 4.22*

53.92 ± 4.12*

89.9

65.9 (25.6)

Role

54.44 ± 4.28

60.57 ± 6.01

47.06 ± 5.91

83.3

55.5 (34.5)

Emotional

59.52 ± 3.31

59.96 ± 4.24

58.99 ± 5.29

82.8

67.3 (24.1)

Cognitive

70.22 ± 3.18

76.02 ± 4.15

63.24 ± 4.71

86.5

81.6 (22.7)

Social

55.33 ± 3.77

51.22 ± 5.35

60.29 ± 5.22

85.8

69.8 (30.3)

Symptom Scales ^b

Fatigue

52.00 ± 3.55

45.26 ± 4.63*

60.29 ± 5.22*

28.8

44.2 (27.5)

Nausea

15.78 ± 2.53

14.63 ± 3.30

17.16 ± 3.95

4

10.8 (19.1)

Pain

53.33 ± 4.38

48.37 ± 6.10

59.31 ± 6.22

20.5

34.7 (32.3)

Single Items ^b

Dyspnoea

46.22 ± 3.79

36.58 ± 4.33*

57.84 ± 6.02*

14.3

40.7 (32.2)

Insomnia

44.00 ± 3.91

39.84 ± 4.97

49.02 ± 6.17

20.4

34.8 (33.4)

Appetite Loss

39.11 ± 3.97

33.33 ± 4.94

46.08 ± 6.30

7.5

31.1 (34.6)

Constipation

29.33 ± 3.90

26.83 ± 4.83

32.35 ± 6.37

10.4

22.2 (31.7)

Diarrhea

7.11 ± 2.03

5.69 ± 2.83

8.82 ± 2.92

9.4

7.3 (18.1)