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Table 1 Breast tumor invasiveness in polyoma middle T (PyMT) transgenic mice positive or negative for mitochondrial targeted catalase (mCAT).

From: Mitochondrial targeted catalase suppresses invasive breast cancer in mice

PyMT Genotype Number of
mice
Primary tumor
incidence
Average Invasion
Grade
Metastatic tumor
incidence
Metastatic tumor
burdena
WT 23 100% 2.8 ± 0.5 85.4% 1.3 ± 0.3
mCAT 32 97% 1.8 ± 0.5*b 56.0%** 0.1 ± 0.02***
  1. a) Metastatic tumor burden expressed as mm2 tumor/cm2 lung. b) Significant at P ≤ 0.03*; P ≤ 0.05**, or P ≤ 0.01***.
  2. Mice were from two separate experiments that were each terminated at 110 days of age.