Figure 6
From: Mitochondrial targeted catalase suppresses invasive breast cancer in mice
Phosphorylation of p38MAPK is decreased in the presence of mCAT. A. Immunoblot of total protein extract from MCAT (Tg/+) and WT (+/+) primary tumor cells. B. Immunoblot of total protein extract from MCAT (Tg/+) and WT (+/+) lung fibroblasts, treated for 4 hours with 0, 100 and 500 μMH2. Lung fibroblast cells expressing mCAT attenuate phosphorylation of p38MAP kinase in the presence of increased levels of oxidative stress. ***p < 0.0001.