Table 2 Immunohistochemical findings for each of the three characteristic components of the tumor.
From: Literature survey on epidemiology and pathology of gangliocytic paraganglioma
| Â | Epithelioid cells | Spindle-shaped cells | Ganglion-like cells |
|---|---|---|---|
S-100 | 3.8% (4/104) | 94.2% (98/104) | 9.3% (9/97) |
Synaptophysin | 90.0% (36/40) | 64.7% (22/34) | 94.3% (33/35) |
Chromogranin A | 67.4% (60/89) | 7.2% (6/83) | 15.4% (12/78) |
Neuron specific enolase | 93.9% (77/82) | 84.0% (63/75) | 84.0% (63/75) |
Cytokeratins | 48.3% (28/58) | 4.0% (2/50) | 3.9% (2/51) |
Vimentin | 14.3% (1/7) | 50.0% (2/4) | 0.0% (0/6) |
Neuron fiber | 20.9% (14/67) | 66.7% (44/66) | 24.6% (16/65) |
Pancreatic polypeptide | 89.7% (70/78) | 0.0% (0/72) | 22.2% (16/72) |
Somatostatin | 81.8% (63/77) | 8.7% (6/69) | 44.1% (30/68) |
Serotonin | 22.0% (13/59) | 0.0% (0/55) | 16.7% (9/54) |
Vasoactive intestinal polypeptide | 12.1% (4/33) | 12.9% (4/31) | 9.7% (3/31) |
Glucagon | 6.4% (3/47) | 0.0% (0/44) | 2.4% (1/42) |
Gastrin | 5.9% (4/68) | 0.0% (0/64) | 0.0% (0/63) |
Insulin | 2.2% (1/46) | 0.0% (0/41) | 0.0% (0/42) |