Table 2 The associations between Ku70 polymorphisms and gastric cancer risk
From: Genetic polymorphisms of DNA double strand break gene Ku70 and gastric cancer in Taiwan
| Â | Case (%) | Control (%) | Adjusted ORa (95% CI) | P -value |
|---|---|---|---|---|
promoter T-991C (rs5751129) | Â | Â | Â | Â |
TT | 106 (77.9) | 502 (89.6) | 1.00 (ref) | Â |
TC | 26 (19.1) | 52 (9.3) | 2.41 (1.53-3.88) | 0.0020 |
CC | 4 (3.0) | 6 (1.1) | 3.21 (0.96-9.41) | 0.0837 |
   P for trend |  |  | 2.87 (1.37-5.02) | <0.0001 |
   (TC+CC) vs TT |  |  | 2.48 (1.74-3.92) | 0.0005 |
   CC vs (TT+TC) |  |  | 2.67 (0.71-9.69) | 0.1114 |
Promoter G-57C (rs2267437) | Â | Â | Â | Â |
CC | 95 (69.9) | 383 (68.4) | 1.00 (ref) | Â |
CG | 37 (27.2) | 167 (29.8) | 0.91 (0.48-1.38) | 0.6722 |
GG | 4 (2.9) | 10 (1.8) | 1.56 (0.55-4.97) | 0.4954 |
   P for trend |  |  | 0.93 (0.53-3.34) | 0.6164 |
   (CG+GG) vs CC |  |  | 0.98 (0.63-1.52) | 0.8367 |
   GG vs (CC+CG) |  |  | 1.52 (0.58-5.01) | 0.4917 |
promoter A-31G (rs132770) | Â | Â | Â | Â |
GG | 109 (80.1) | 459 (82.0) | 1.00 (ref) | Â |
GA | 19 (14.0) | 73 (13.0) | 1.16 (0.71-1.93) | 0.7763 |
AA | 8 (5.9) | 28 (5.0) | 1.25 (0.51-2.68) | 0.6642 |
   P for trend |  |  | 1.18 (0.68-2.34) | 0.9065 |
   (GA+AA) vs GG |  |  | 1.14 (0.73-1.76) | 0.6227 |
   AA vs (GG+GA) |  |  | 1.03 (0.37-3.01) | 0.6673 |
intron 3 (rs132774) | Â | Â | Â | Â |
GG | 113 (83.1) | 459 (82.0) | 1.00 (ref) | Â |
GC | 23 (16.9) | 101 (18.0) | 0.91 (0.60-1.73) | 0.8040 |
CC | 0 (0.0) | 0 (0.0) | Â | Â |