Figure 4From: Metabolic markers in relation to hypoxia; staining patterns and colocalization of pimonidazole, HIF-1α, CAIX, LDH-5, GLUT-1, MCT1 and MCT4 Colocalization of the various markers. (a-d) CAIX, LDH-5 and MCT4 show a significantly higher expression in pimonidazole stained areas, MCT1 expression is not significantly different. (e and f) Expression of MCT1 and MCT4 in CAIX negative and positive areas, both are significantly higher in areas expressing CAIX. (g and h) Increased expression of MCT1 and GLUT in MCT4 positive areas.Back to article page