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Table 1 Characteristics of patient groups

From: Growth of breast cancer recurrences assessed by consecutive MRI

 

Primary

breast cancer

Recurrence

of breast

cancer

Ipsilateral

recurrence

Contralateral recurrence

P

Characteristic

(n = 20)

(n = 17)

(n = 7)

(n = 10)

 

Age at detection (years)

     

   Median (range)

56 (40-72)

60 (44-78)

57 (53-64)

62 (44-78)

0.61

Menopausal status

     

   Pre-

6 (30%)

1 (6%)

1 (14%)

0 (0%)

 

   Post-, with HT

3 (15%)

0 (0%)

0 (0%)

0 (0%)

0.11

   Post-, without HT

11 (55%)

16 (94%)

6 (86%)

10 (100%)

 

Mutation

     

   BRCA 1

2 (10%)

0 (0%)

0 (0%)

0 (0%)

0.24

   BRCA 2

0 (0%)

1 (5.9%)

1 (14%)

0 (0%)

 

Delay between cancers

     
  

10 (2 - 19)

13 (9-19)

8 (2-17)

.003

Histologic type of primary cancer

 

   IDC/ILC

 

12 (75%)

6/7 (86%)

6/9 (67%)

 

   DCIS

 

4 (25%)

1/7 (14%)

3/9 (33%)

 

Treatment of primary breast cancer

 

Surgery

    

0.48

   Breast-conserving surgery

 

15 (88%)

7/7 (100%)

8/10 (80%)

 

   Mastectomy

 

2 (12%)

0/7 (0%)

2/10 (20%)

 

Radiotherapy

 

16 (94%)

7/7 (100%)

9/10 (90%)

1

Chemotherapy

 

8 (47%)

2/7 (29%)

6/10 (60%)

0.33

Hormonal therapy

 

4 (27%)

1/6 (17%)

3/9 (33%)

0.60

Location of cancer

     

   Inner

3 (15%)

5 (29%)

1 (14%)

4 (40%)

 

   Central

4 (20%)

1 (6%)

1 (14%)

0 (0%)

0.43

   Outer

13 (65%)

11 (65%)

5 (17%)

6 (60%)

 

Histology of new cancer

1.00

   Invasive carcinoma

18 (90%)

15 (88%)

6 (86%)

9 (90%)

 

SBR 1

9 (50%)

4 (22%)

2 (33%)

2 (22%)

 

SBR 2

5 (28%)

9 (60%)

3 (50%)

6 (67%)

0.51

SBR 3

4 (22%)

2 (13%)

1 (7%)

1 (11%)

 

   DCIS

2 (10%)

2 (12%)

1 (14%)

1 (10%)

 

Tumour size

     

   Maximum tumour diameter at pathologic review (mm)

9

(0 - 28)

10

(2 - 35)

10

(2 - 18)

8.5

(5 - 35)

0.97

   Initial volume (mm3)

244 (14 - 4837)

121 (8 - 2806)

121 (26 - 612)

116 (8 - 2806)

0.44

   Final volume (mm3)

357 (36 - 4373)

425 (68 - 4319)

359 (100 - 1355)

458 (68 - 4319)

0.90

Hormone receptors

     

   Oestrogen receptors

80 (0-100)

95 (20 - 100)

90 (60 - 100)

100 (20 - 100)

0.06

   Progesterone receptors

30 (0 - 95)

40 (0 - 95)

25 (2 - 95)

55 (0 - 90)

0.99

Ki67

     

   Median (range)

6 (1 - 35)

12 (2 - 40)

12 (5 - 30)

12.5 (2 - 40)

0.09

Mitotic count

     

   Median (range)

2 (0 - 31)

7 (1 - 20)

3.5 (1 - 10)

9 (1 - 20)

0.20