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Table 1 Characteristics of patient groups

From: Growth of breast cancer recurrences assessed by consecutive MRI

  Primary
breast cancer
Recurrence
of breast
cancer
Ipsilateral
recurrence
Contralateral recurrence P
Characteristic (n = 20) (n = 17) (n = 7) (n = 10)  
Age at detection (years)      
   Median (range) 56 (40-72) 60 (44-78) 57 (53-64) 62 (44-78) 0.61
Menopausal status      
   Pre- 6 (30%) 1 (6%) 1 (14%) 0 (0%)  
   Post-, with HT 3 (15%) 0 (0%) 0 (0%) 0 (0%) 0.11
   Post-, without HT 11 (55%) 16 (94%) 6 (86%) 10 (100%)  
Mutation      
   BRCA 1 2 (10%) 0 (0%) 0 (0%) 0 (0%) 0.24
   BRCA 2 0 (0%) 1 (5.9%) 1 (14%) 0 (0%)  
Delay between cancers      
   10 (2 - 19) 13 (9-19) 8 (2-17) .003
Histologic type of primary cancer  
   IDC/ILC   12 (75%) 6/7 (86%) 6/9 (67%)  
   DCIS   4 (25%) 1/7 (14%) 3/9 (33%)  
Treatment of primary breast cancer  
Surgery      0.48
   Breast-conserving surgery   15 (88%) 7/7 (100%) 8/10 (80%)  
   Mastectomy   2 (12%) 0/7 (0%) 2/10 (20%)  
Radiotherapy   16 (94%) 7/7 (100%) 9/10 (90%) 1
Chemotherapy   8 (47%) 2/7 (29%) 6/10 (60%) 0.33
Hormonal therapy   4 (27%) 1/6 (17%) 3/9 (33%) 0.60
Location of cancer      
   Inner 3 (15%) 5 (29%) 1 (14%) 4 (40%)  
   Central 4 (20%) 1 (6%) 1 (14%) 0 (0%) 0.43
   Outer 13 (65%) 11 (65%) 5 (17%) 6 (60%)  
Histology of new cancer 1.00
   Invasive carcinoma 18 (90%) 15 (88%) 6 (86%) 9 (90%)  
SBR 1 9 (50%) 4 (22%) 2 (33%) 2 (22%)  
SBR 2 5 (28%) 9 (60%) 3 (50%) 6 (67%) 0.51
SBR 3 4 (22%) 2 (13%) 1 (7%) 1 (11%)  
   DCIS 2 (10%) 2 (12%) 1 (14%) 1 (10%)  
Tumour size      
   Maximum tumour diameter at pathologic review (mm) 9
(0 - 28)
10
(2 - 35)
10
(2 - 18)
8.5
(5 - 35)
0.97
   Initial volume (mm3) 244 (14 - 4837) 121 (8 - 2806) 121 (26 - 612) 116 (8 - 2806) 0.44
   Final volume (mm3) 357 (36 - 4373) 425 (68 - 4319) 359 (100 - 1355) 458 (68 - 4319) 0.90
Hormone receptors      
   Oestrogen receptors 80 (0-100) 95 (20 - 100) 90 (60 - 100) 100 (20 - 100) 0.06
   Progesterone receptors 30 (0 - 95) 40 (0 - 95) 25 (2 - 95) 55 (0 - 90) 0.99
Ki67      
   Median (range) 6 (1 - 35) 12 (2 - 40) 12 (5 - 30) 12.5 (2 - 40) 0.09
Mitotic count      
   Median (range) 2 (0 - 31) 7 (1 - 20) 3.5 (1 - 10) 9 (1 - 20) 0.20