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Table 1 ED50 values for DHA and curcumin effects on breast cancer cell lines.

From: A synergistic antiproliferation effect of curcumin and docosahexaenoic acid in SK-BR-3 breast cancer cells: unique signaling not explained by the effects of either compound alone

    Combination
  Initial ED50(μM)a Ratio (μM)
Cell Line DHA CCM DHA:CCM
MCF7 56.5 ± 8.2 28.0 ± 4.2 55:30
MCF10AT 93.2 ± 5.5 45.8 ± 2.5 95:45
MDA-MB-231 36.7 ± 6.5 34.7 ± 10.4 35:35
SK-BR-3 63.8 ± 1.5 39.2 ± 1.8 60:40
MDA-MB-361 52.5 ± 9.5 23.0 ± 4.2 50:25
  1. aInitial ED50 values calculated as mean ± SD concentration required for 50% inhibition of proliferation from two independent triplicate assays.