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Table 1 ED50 values for DHA and curcumin effects on breast cancer cell lines.

From: A synergistic antiproliferation effect of curcumin and docosahexaenoic acid in SK-BR-3 breast cancer cells: unique signaling not explained by the effects of either compound alone

   

Combination

 

Initial ED50(μM)a

Ratio (μM)

Cell Line

DHA

CCM

DHA:CCM

MCF7

56.5 ± 8.2

28.0 ± 4.2

55:30

MCF10AT

93.2 ± 5.5

45.8 ± 2.5

95:45

MDA-MB-231

36.7 ± 6.5

34.7 ± 10.4

35:35

SK-BR-3

63.8 ± 1.5

39.2 ± 1.8

60:40

MDA-MB-361

52.5 ± 9.5

23.0 ± 4.2

50:25

  1. aInitial ED50 values calculated as mean ± SD concentration required for 50% inhibition of proliferation from two independent triplicate assays.
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BMC Cancer

ISSN: 1471-2407

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