Table 3 Expression analysis of NDRG2 using a cancer profiling array
Tissue | Number of samples | Paired two-tailed t-test | Down-regulated (Tumor/normal ratio ≤ 0.5) | Unaltered (Tumor/normal ratio between 0.51-1.99) | Up-regulated (Tumor/normal ratio ≥ 2.0) | Benjamini-Hochberg correction |
|---|---|---|---|---|---|---|
Down-regulated NDRG2mRNA levels | ||||||
Liver | 3 | NS | 3 | - | - | NS |
Down-regulated or unaltered NDRG2 mRNA levels | ||||||
Cervix | 10 | 0.023 | 3 | 7 | - | NS |
Colon | 10 | 0.008 | 4 | 6 | - | NS |
Ovary | 10 | NS | 3 | 7 | - | NS |
Skin | 10 | NS | 4 | 6 | - | NS |
Testis | 10 | 0.030 | 7 | 3 | - | NS |
Thyroid Gland | 10 | 0.005 | 5 | 5 | - | NS |
Vulva | 5 | NS | 2 | 3 | - | NS |
Unaltered NDRG2 mRNA levels | ||||||
Prostate | 4 | NS | - | 4 | - | NS |
Small Intestine | 7 | NS | - | 7 | - | NS |
Trachea | 3 | NS | - | 3 | - | NS |
Unaltered or up-regulated NDRG2 mRNA levels | ||||||
Bladder | 5 | NS | - | 3 | 2 | NS |
Stomach | 10 | NS | - | 8 | 2 | NS |
Down-regulated, unaltered or up-regulated NDRG2 mRNA levels | ||||||
Breast | 10 | NS | 4 | 5 | 1 | NS |
Kidney | 10 | NS | 3 | 4 | 3 | NS |
Lung | 10 | NS | 1 | 8 | 1 | NS |
Pancreas | 7 | NS | 1 | 5 | 1 | NS |
Rectum | 10 | NS | 3 | 6 | 1 | NS |
Uterus | 10 | NS | 3 | 5 | 2 | NS |