Skip to main content

Table 5 The comparisons of EORTC QLQ-C30 and H&N35 scales for head and neck cancer survivors at different tumor sites

From: Health-related Quality of life in 640 head and neck cancer survivors after radiotherapy using EORTC QLQ-C30 and QLQ-H&N35 questionnaires

  Nasopharynx
(n = 316)
Oral cavity
(n = 129)
Oropharynx
(n = 75)
Hypropharynx
&Larynx(n = 120)
 
  Mean (SD) Mean (SD) Mean (SD) Mean (SD) p
EORTC QLQ-C30      
   Global quality of life 53.7 (20.4) 56.1 (16.7) 55.2 (21.6) 54.8 (20.9) NS
   Physical functioning 85.7 (16.3) 86.4 (13.8)e 82.2 (16.9) 80.9 (18.7)c 0.015
   Role functioning 88.7 (19.5) 87.0 (19.1) 83.6 (22.1) 81.2 (25.0)c <0.01
   Emotional functioning 78.0 (19.7) 79.9 (18.6) 75.3 (22.7) 77.0 (20.8) NS
   Cognitive functioning 77.8 (18.7) 82.8 (19.2)d 75.1 (23.0) 76.9 (20.9) 0.025
   Social functioning 77.0 (23.2) 75.4 (22.8) 73.1 (27.0) 71.0 (25.8) NS
   Fatigue 29.6 (19.8) 24.9 (21.2)d 32.7 (19.2) 30.4 (21.4) 0.037
   Nausea/Vomiting 8.4 (15.6) 6.2 (14.2)d, e 13.5 (22.5) 12.4 (20.8) <0.01
   Pain 20.8 (21.5) 19.2 (23.1) 26.8 (21.9) 24.9 (23.8) 0.038
   Dyspnea 12.7 (19.9) 12.4 (20.4)e 17.8 (23.5) 23.6 (24.0)c <0.01
   Insomnia 25.1 (26.3) 23.1 (25.5) 30.1 (22.8) 30.7 (26.5) 0.049
   Appetite loss 17.0 (23.8) 17.9 (24.3)d 30.7 (26.0)b 23.1 (24.1) <0.01
   Constipation 16.5 (22.4) 18.4 (22.4) 23.7 (26.8) 24.0 (25.3)c <0.01
   Diarrhea 13.4 (18.9) 12.2 (18.6) 16.4 (26.0) 15.9 (19.3) NS
   Financial problems 23.4 (26.4) 26.9 (25.7) 31.9 (29.9) 30.5 (27.9) 0.023
EORTC QLQ-HN35      
   Pain 17.0 (18.3) 17.3 (22.9)d 27.4 (20.7)b 21.5 (22.5) <0.01
   Swallowing 26.8 (22.4) 30.6 (25.4) 38.0 (23.6)b 33.8 (27.5)c <0.01
   Senses (taste/smell) 27.2 (27.0) 22.1 (26.8) 26.4 (27.4) 31.3 (30.1) NS
   Speech 23.0 (23.3) 25.6 (21.8)e 32.0 (27.1)b 41.3 (30.7)c <0.01
   Social eating 24.1 (24.9) 33.2 (27.0)a 35.4 (27.8)b 30.7 (29.5) <0.01
   Social contact 15.4 (19.9) 24.0 (23.2)a 23.9 (26.7)b 27.5 (27.4)c <0.01
   Sexuality 23.8 (27.6) 24.3 (24.4) 30.5 (29.4) 31.3 (29.5) 0.035
   Teeth 38.1 (28.3) 41.0(31.8) 42.7 (30.2) 36.1 (31.3) NS
   Opening mouth 30.1 (29.7) 43.9 (34.2)a, e 37.8 (32.9)f 25.1 (29.4) <0.01
   Dry mouth 53.5 (31.3) 45.9 (30.7) 49.2 (30.6)f 36.6 (27.5)c <0.01
   Sticky saliva 42.8 (31.7) 37.6 (28.4) 46.3 (29.8) 35.0 (29.8) 0.024
   Coughing 25.9 (23.9) 23.9 (23.3)e 31.5 (27.4)f 43.1 (25.4)c <0.01
   Feeling ill 29.6 (25.5) 24.8 (23.7) 31.5 (25.1) 32.1 (26.0) NS
  1. a : p < 0.05, Oral cavity compared with Nasopharynx; b : p < 0.05, Oropharynx compared with Nasopharynx; c : p < 0.05, Hypropharynx & Larynx compared with Nasopharynx; d : p < 0.05, Oral cavity compared with Oropharynx; e : p < 0.05, Oral cavity compared with Hypropharynx & Larynx; f : p < 0.05, Oropharynx compared with Hypropharynx & Larynx