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Table 3 Association between KLK15 Single Nucleotide Polymorphisms and ovarian cancer survival in Australian dataset

From: A Kallikrein 15 (KLK15) single nucleotide polymorphism located close to a novel exon shows evidence of association with poor ovarian cancer survival

KLK15

n

n censored

Adjusted* HR (95% CI)

p value (trend)

rs2659058

    

TT

123

74

1.0

 

CT

138

88

1.13 (0.82-1.55)

0.75

CC

50

26

1.20 (0.75-1.91)

 

rs3212810

    

CC

207

122

1.0

 

TC

87

51

1.01 (0.72-1.41)

0.29

TT

18

14

1.46 (0.82-2.62)

 

rs3745522

    

GG

187

106

1.0

 

GT

81

48

0.97 (0.68-1.39)

0.15

TT

18

13

1.73 (0.93-3.24)

 

rs266851

    

CC

222

128

1.0

 

CT

89

55

1.43 (1.02-2.00)

 

TT

7

5

1.26 (0.49-3.24)

0.01

CT/TT

96

60

1.42 (1.02-1.96)

 

rs2659055

    

TT

84

52

1.0

0.23

TC

144

87

0.86 (0.60-1.23)

 

CC

67

36

0.74 (0.47-1.17)

 

rs190552

    

TT

178

109

1.0

0.79

CT

114

65

1.04 (0.76-1.42)

 

CC

19

13

1.21 (0.67-2.17)

 

rs2739442

    

GG

92

55

1.0

0.99

GA

133

76

1.09 (0.75-1.58)

 

AA

89

54

1.08 (0.73-1.62)

 

rs2659053

    

GG

129

79

1.0

0.2

GA

118

73

0.93 (0.66-1.29)

 

AA

63

34

0.95 (0.63-1.44)

 

rs2569746

    

AA

111

65

1.0

0.43

TA

119

74

0.90 (0.64-1.27)

 

TT

57

36

1.12 (0.74-1.69)

 
  1. *Adjusted for age, FIGO stage, histological subtype, and grade.