Table 4 Cytotoxic effect of LTX-302, LTX-315 and LTX-318 against CHO-K1 and pgsA-745 cells.
From: Small lytic peptides escape the inhibitory effect of heparan sulfate on the surface of cancer cells
Peptide | CHO-K1 a IC 50 (μM) | pgsA-745 a IC 50 (μM) | Ratio (IC 50 ) pgsA-745/CHO-K1 |
|---|---|---|---|
LTX-302 | 42 ± 7 | 54 ± 2 | 1.28 |
LTX-315 | 22 ± 5 | 22 ± 3 | 1.00 |
LTX-318 | 145 ± 6 | 176 ± 3 | 1.21 |