Table 1 Patient characteristics
Characteristic | Patients (n = 107) | |
|---|---|---|
| Â | No. | (%) |
Age, Years | Â | Â |
   Median | 62 | |
   Range | 38-82 | |
Gender | Â | Â |
   Female | 49 | (46) |
   Male | 58 | (54) |
ECOG performance status | Â | Â |
   0 | 55 | (51) |
   1 | 42 | (39) |
   2 | 10 | (10) |
No. of prior chemotherapy regimes for metastatic disease | Â | Â |
   2 | 79 | (74) |
   3 | 27 | (25) |
   NA | 1 | (1) |
Primary surgery for CRC | Â | Â |
   Yes | 97 | (91) |
   No | 9 | (8) |
   NA | 1 | (1) |
Pre-operative chemoradiation | Â | Â |
   Yes | 17 | (16) |
   No | 88 | (82) |
   NA | 2 | (2) |
Anatomic site | Â | Â |
   Colon | 40 | (37) |
   Rectosignoideum | 36 | (34) |
   Rectum | 39 | (36) |
   NA | 3 | (3) |
No. of metastatic sites | Â | Â |
   1-2 | 48 | (45) |
   3-5 | 57 | (53) |
   NA | 1 | (1) |
No of cycles | ||
   Median | 6 | |
   Range | 1-18 | |
Best response | ||
   PR | 20 | (19) |
   SD | 35 | (33) |
   PD | 31 | (29) |
   Clinical progression* | 17 | (16) |
   NA | 4 | (4) |
Worst Toxicity/Rash grade | ||
   0 | 15 | (14) |
   1 | 41 | (39) |
   2 | 19 | (18) |
   3 | 11 | (13) |
   NA | 25 | (23) |