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Table 2 Analysis of association between APE1/Ref-1 rs1760944 and risk of all gliomas

From: A genetic variant in the APE1/Ref-1 gene promoter -141T/G may modulate risk of glioblastoma in a Chinese Han population

rs1760944

Controls (824)

All Gliomas (766)

 

No. (%)

No. (%)

P a

OR (95% CI) b

P c

Alleles

     

T

898 (55.0)

858 (57.2)

0.220

1.00 (reference)

0.220

G

734 (45.0)

642 (42.8)

 

0.91 (0.79-1.05)

 

Genotypes

     

TT

237 (29.0)

233 (30.4)

0.410

1.00 (reference)

 

TG

424 (52.0)

392 (51.2)

 

0.94 (0.75-1.18)

0.588

GG

155 (19.0)

125 (16.3)

 

0.81 (0.61-1.10)

0.183

   

P d for trend = 0.199

  1. aAllele and genotype frequencies in cases and controls were compared using χ2 test.
  2. bAllele-specific OR was not adjusted; genotype-specific ORs were adjusted for age and gender.
  3. c P value from unconditional logistic regression analyses.
  4. dTrend test was calculated using the genotype as an ordinal variable in the regression model.
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BMC Cancer

ISSN: 1471-2407

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