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Table 3 Cox multivariate regression analysis of PINCH expression at tumour invasive margin, sex, age and stage in poorly differentiated tumours in relation to patient survival in colorectal cancer

From: Impact of PINCH expression on survival in colorectal cancer patients

Variable

N (%)

Death (%)

HR

95% CI

P-value

PINCH expression

     

   Weak

50 (55)

30 (60)

1.00

-

-

   Strong

41 (45)

36 (88)

1.90

1.14-3.16

0.013

Sex

     

   Male

48 (53)

34 (71)

1.00

-

-

   Female

43 (47)

32 (74)

1.10

0.67-1.81

0.69

Age (years)

     

   ≤ 69

51 (56)

40 (78)

1.00

-

-

   > 69

40 (44)

26 (65)

1.37

0.81-2.32

0.24

Stage

     

   I+II

18 (20)

7 (39)

1.00

-

-

   III

38 (42)

26 (68)

2.75

1.16-6.56

0.022

   IV

35 (38)

33 (94)

9.09

3.63-22.75

< 0.0001

  1. HR: Hazard ratio; 95% CI: 95% confidence interval. (69 years = median age at operation)