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Table 3 Cox multivariate regression analysis of PINCH expression at tumour invasive margin, sex, age and stage in poorly differentiated tumours in relation to patient survival in colorectal cancer

From: Impact of PINCH expression on survival in colorectal cancer patients

Variable N (%) Death (%) HR 95% CI P-value
PINCH expression      
   Weak 50 (55) 30 (60) 1.00 - -
   Strong 41 (45) 36 (88) 1.90 1.14-3.16 0.013
Sex      
   Male 48 (53) 34 (71) 1.00 - -
   Female 43 (47) 32 (74) 1.10 0.67-1.81 0.69
Age (years)      
   ≤ 69 51 (56) 40 (78) 1.00 - -
   > 69 40 (44) 26 (65) 1.37 0.81-2.32 0.24
Stage      
   I+II 18 (20) 7 (39) 1.00 - -
   III 38 (42) 26 (68) 2.75 1.16-6.56 0.022
   IV 35 (38) 33 (94) 9.09 3.63-22.75 < 0.0001
  1. HR: Hazard ratio; 95% CI: 95% confidence interval. (69 years = median age at operation)