Table 2 Cox multivariate regression analysis of PINCH expression in adjacent normal mucosa, sex, age, tumour location, grade of differentiation and stage in relation to patient survival in colorectal cancer

PINCH expression

   Weak

102 (70)

52 (51)

1.00

-

-

   Strong

44 (30)

35 (80)

1.60

1.01-2.53

0.044

Sex

   Male

83 (57)

52 (63)

1.00

-

-

   Female

63 (43)

35 (56)

0.82

0.53-1.28

0.39

Age (years)

   ≤ 69

70 (48)

46 (66)

1.00

-

-

   > 69

76 (52)

41 (53)

1.51

0.96-2.39

0.075

Tumour Location

   Colon

77 (53)

46 (60)

1.00

-

-

   Rectum

69 (47)

41 (59)

1.16

0.75-1.79

0.51

Differentiation

   Well+moderate+poor

121 (83)

71 (59)

1.00

-

-

   Mucinous

25 (17)

16 (64)

0.95

0.55-1.65

0.85

Stage

   I

17 (12)

3 (18)

1.00

-

-

   II

34 (23)

15 (44)

3.32

0.95-11.62

0.061

   III

64 (44)

40 (63)

6.98

2.11-23.06

0.0014

   IV

31 (21)

29 (94)

28.71

8.24-100.03

< 0.0001