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Table 2 Cox multivariate regression analysis of PINCH expression in adjacent normal mucosa, sex, age, tumour location, grade of differentiation and stage in relation to patient survival in colorectal cancer

From: Impact of PINCH expression on survival in colorectal cancer patients

Variable N (%) Death (%) HR 95% CI P-value
PINCH expression      
   Weak 102 (70) 52 (51) 1.00 - -
   Strong 44 (30) 35 (80) 1.60 1.01-2.53 0.044
Sex      
   Male 83 (57) 52 (63) 1.00 - -
   Female 63 (43) 35 (56) 0.82 0.53-1.28 0.39
Age (years)      
   ≤ 69 70 (48) 46 (66) 1.00 - -
   > 69 76 (52) 41 (53) 1.51 0.96-2.39 0.075
Tumour Location      
   Colon 77 (53) 46 (60) 1.00 - -
   Rectum 69 (47) 41 (59) 1.16 0.75-1.79 0.51
Differentiation      
   Well+moderate+poor 121 (83) 71 (59) 1.00 - -
   Mucinous 25 (17) 16 (64) 0.95 0.55-1.65 0.85
Stage      
   I 17 (12) 3 (18) 1.00 - -
   II 34 (23) 15 (44) 3.32 0.95-11.62 0.061
   III 64 (44) 40 (63) 6.98 2.11-23.06 0.0014
   IV 31 (21) 29 (94) 28.71 8.24-100.03 < 0.0001
  1. HR: Hazard ratio; 95% CI: 95% confidence interval. (69 years = median age at operation)