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Table 5 Effect of tobacco and XPC, ERCC2 and ERCC5 polymorphisms on pT1 tumors grade

From: The effect of tobacco, XPC, ERCC2 and ERCC5 genetic variants in bladder cancer development

        

95% Confidence Interval for Exp(B)

grade a

B

Std. Error

Wald

df

Sig.

Exp(B)

Lower Bound

Upper Bound

III

Intercept

,38

3,21

,01

1

,91

   
 

Sex

-1,20

1,42

,72

1

,40

,30

,02

4,84

 

Age

,55

,78

,49

1

,48

1,73

,37

8,05

 

[XPC (A/C) = AA]

-,01

,82

,00

1

,98

,98

,20

4,90

 

[XPC (A/C) = AC]

,14

,75

,03

1

,86

1,15

,26

4,98

 

[XPC (A/C) = CC]

0b

.

.

0

.

.

.

.

 

[ERCC2 (A/C) = AA]

,43

,92

,21

1

,64

1,53

,25

9,30

 

[ERCC2 (A/C) = AC]

-,29

,97

,09

1

,76

,74

,11

4,96

 

[ERCC2 (A/C) = CC]

0b

.

.

0

.

.

.

.

 

[ERCC5 (G/C) = CC]

,58

,89

,42

1

,52

1,78

,31

10,26

 

[ERCC5 (G/C) = GC]

-,08

,58

,02

1

,89

,92

,30

2,88

 

[ERCC5 (G/C) = GG]

0b

.

.

0

.

.

.

.

 

[PY = 0]

1,93

,82

5,54

1

,02

6,89

1,38

34,33

 

[PY = 1-19]

-18,32

,00

.

1

.

1,10

1,10

1,10

 

[PY ≥ 20]

0b

.

.

0

.

.

.

.

  1. This model was obtained after adjustment to sex and age; a: The reference category is pT1 with Grade II tumor; b: this parameter is set to zero because it is redundant; PY: pack years. Logistic regression: Number of observation = 87, Chi-square: 24.173, p = 0.007, Pseudo R-square = 0.213, Log likelihood = 57.865