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Table 3 Case-control study: implication of tobacco and polymorphisms in XPC, ERCC2 and ERCC5 on bladder cancer development

From: The effect of tobacco, XPC, ERCC2 and ERCC5 genetic variants in bladder cancer development

        

95% Confidence Interval for Exp(B)

groupa

B

Standard error

Wald

Df

P value

Exp (B) = OR

Lower Bound

Upper Bound

Cases

Intercept

-1,10

1,08

1,03

1

,31

   
 

Sex

,30

,42

,53

1

,46

1,36

,59

3,11

 

Age range

1,82

,39

21,99

1

,00

6,22

2,89

13,35

 

[XPC (A/C) = AA]

-,85

,34

6,06

1

,01

,42

,21

,84

 

[XPC (A/C) = AC]

-1,01

,34

8,80

1

,00

,36

,18

,70

 

[XPC (A/C) = CC]

0b

.

.

0

.

.

.

.

 

[ERCC2 (A/C) = AA]

,12

,40

,10

1

,75

1,13

,51

2,51

 

[ERCC2 (A/C) = AC]

-,16

,40

,15

1

,69

,85

,38

1,90

 

[ERCC2 (A/C) = CC]

0b

.

.

0

.

.

.

.

 

[ERCC5 (G/C) = CC]

,55

,38

2,11

1

,14

1,74

,82

3,71

 

[ERCC5 (G/C) = GC]

-,22

,24

,85

1

,35

,79

,49

1,29

 

[ERCC5 (G/C) = GG]

0b

.

.

0

.

.

.

.

 

[Tobacco PY = 0]

-1,18

,32

13,03

1

,00

,30

,16

,58

 

[Tobacco PY = 1-19]

-1,97

,45

19,17

1

,00

,13

,05

,33

 

[Tobacco PY ≥ 20]

0b

.

.

0

.

.

.

.

  1. This reduced model was obtained after adjustment to sex and age; a: The reference category is controls group; b: this parameter is set to zero because it is redundant; PY: pack years. Logistic regression: Number of observation = 386, Chi-square: 88.409, p = 0.000, Pseudo R-square = 0.205, Log likelihood = 206,541