Table 3 Case-control study: implication of tobacco and polymorphisms in XPC, ERCC2 and ERCC5 on bladder cancer development

95% Confidence Interval for Exp(B)
groupa B Standard error Wald Df P value Exp (B) = OR Lower Bound Upper Bound
Cases Intercept -1,10 1,08 1,03 1 ,31
Sex ,30 ,42 ,53 1 ,46 1,36 ,59 3,11
Age range 1,82 ,39 21,99 1 ,00 6,22 2,89 13,35
[XPC (A/C) = AA] -,85 ,34 6,06 1 ,01 ,42 ,21 ,84
[XPC (A/C) = AC] -1,01 ,34 8,80 1 ,00 ,36 ,18 ,70
[XPC (A/C) = CC] 0b . . 0 . . . .
[ERCC2 (A/C) = AA] ,12 ,40 ,10 1 ,75 1,13 ,51 2,51
[ERCC2 (A/C) = AC] -,16 ,40 ,15 1 ,69 ,85 ,38 1,90
[ERCC2 (A/C) = CC] 0b . . 0 . . . .
[ERCC5 (G/C) = CC] ,55 ,38 2,11 1 ,14 1,74 ,82 3,71
[ERCC5 (G/C) = GC] -,22 ,24 ,85 1 ,35 ,79 ,49 1,29
[ERCC5 (G/C) = GG] 0b . . 0 . . . .
[Tobacco PY = 0] -1,18 ,32 13,03 1 ,00 ,30 ,16 ,58
[Tobacco PY = 1-19] -1,97 ,45 19,17 1 ,00 ,13 ,05 ,33
[Tobacco PY ≥ 20] 0b . . 0 . . . .
1. This reduced model was obtained after adjustment to sex and age; a: The reference category is controls group; b: this parameter is set to zero because it is redundant; PY: pack years. Logistic regression: Number of observation = 386, Chi-square: 88.409, p = 0.000, Pseudo R-square = 0.205, Log likelihood = 206,541