Skip to main content

Table 2 Comparisons of the XP C, ERCC2 and ERCC5 alleles and genotypes distributions between patients and controls

From: The effect of tobacco, XPC, ERCC2 and ERCC5 genetic variants in bladder cancer development

 

N (%)

  

Alleles and Genotypes

Controls (N = 193)

Patients (N = 193)

P value

OR (95% CI)

XPC (rs2228001)

    

   AA

79 (40.9)

74 (38.3)

-

1*

   AC

92 (47.7)

76 (39.4)

0.65

-

   CC

22 (11.4)

43 (22.3)

0.04**

2.09 (1.09-3.99)

   A

250 (64.8)

224 (58.0)

-

1*

   C

136 (35.2)

162 (42.0)

0.06

-

ERCC2 (rs13181)

    

   AA

86 (44.6)

97 (50.3)

-

1*

   AC

86 (44.6)

76 (39.4)

0.30

-

   CC

21 (10.9)

20 (10.4)

0.75

-

   A

258 (66.8)

270 (69.9)

-

1*

   C

128 (33.2)

116 (30.1)

0.39

-

ERCC5 (rs17655)

    

   GG

87 (45.1)

95 (49.2)

-

1*

   GC

86 (44.6)

70 (36.3)

0.21

-

   CC

20 (10.4)

28 (14.5)

0.55

-

   G

260 (67.3)

260 (67.3)

-

1*

   C

126 (32.7)

126 (32.7)

0.93

-

  1. 95% CI: Confidence Interval, 1*: reference group, **: Corrected p value (Bonferroni's correction)