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Table 4 Tumor response to 2nd EGFR-TKI vs. chemotherapy

From: Clinical responses to EGFR-tyrosine kinase inhibitor retreatment in non-small cell lung cancer patients who benefited from prior effective gefitinib therapy: a retrospective analysis

Characteristics

2nd TKI group

Control group

P

OS from 1st gefitinib

  

   Median

21.5

12.3

0.07

   95% CI

14.6 - 28.4

9.4 - 15.2

 

Response to 2nd TKI or chemotherapy

 

   PR

1

0

 

   SD

7

1

 

   PD

3

4

 

PFS to 2nd TKI or chemotherapy

  

   Median

3.4

2

0.1

   95% CI

2 - 5.2

1.5 - 2.4

 

OS from 2nd TKI or chemotherapy

  

   Median

7.3

2.2

0.12

   95% CI

2.7 - 13

2.2 - 2.8

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