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Table 3 Dietary intakes stratified by BRAF and K-ras mutation status.

From: Dietary, lifestyle and clinicopathological factors associated with BRAF and K-ras mutations arising in distinct subsets of colorectal cancers in the EPIC Norfolk study

 

BRAFmutation

K-rasmutation

Dietary factor

Wildtype n= 156

Mutant n= 29

P ‡

Wildtype n= 144

Mutant n= 41

P ‡

Meat

      

   Red Meat (g/d)

37 (28.9)

40 (24.5)

0.60

38 (28.4)

33 (27.2)

0.31

   Processed Meat (g/d)

24 (19.7)

25 (14.3)

0.81

25 (18.7)

23 (19.8)

0.62

   Red + Processed Meat (g/d)

61 (37.1)

65 (28.5)

0.59

63 (35.9)

56 (35.4)

0.29

   White Meat (g/d)

21 (20.2)

17 (15.5)

0.29

17 (18.0)

30 (22.1)

<0.001

   White Fish (g/d)

17 (15.7)

17 (26.5)

0.98

18 (19.3)

14 (10.7)

0.28

   Fatty Fish (g/d)

12 (20.0)

10 (12.1)

0.64

11 (17.5)

14 (23.4)

0.33

Fruit and vegetables

      

   Fruit (g/d)

170 (133.1)

193 (170.9)

0.42

168 (143.0)

191 (125.8)

0.36

   Vegetables (g/d)

136 (68.3)

150 (70.9)

0.29

136 (66.6)

145 (76.1)

0.43

Fat

      

   Total Fat (g/d)

71 (22.9)

71 (23.7)

1.00

71 (22.4)

75 (25.0)

0.32

   PUFA (g/d)

13 (5.3)

13 (5.7)

0.96

13 (5.1)

14 (6.2)

0.20

   MUFA (g/d)

25 (8.1)

24 (7.5)

0.77

24 (7.9)

26 (8.5)

0.29

   SFA (g/d)

27 (10.2)

28 (11.7)

0.84

27 (10.3)

28 (10.7)

0.59

Vitamins

      

   B2[riboflavin] (mg/d)

2 (0.6)

2 (0.6)

0.95

2 (0.6)

2 (0.6)

0.67

   B3[niacin] (mg/d)

18 (5.5)

18 (6.7)

0.69

18 (5.9)

19 (4.7)

0.40

   B6[pyroxidine] (μg/d)

2 (0.6)

2 (0.6)

0.96

2 (0.6)

2 (0.6)

0.35

   B9[folate] (μg/d)

259 (71.9)

257 (73.8)

0.89

258 (73.4)

260 (67.7)

0.89

   B12 (μg/d)

6 (5.5)

5 (4.0)

0.40

6 (5.2)

6 (5.4)

0.96

   C (mg/d)

85 (48.7)

87 (38.8)

0.82

85 (45.5)

87 (53.4)

0.78

   D (μg/d)

3 (2.2)

4 (2.3)

0.69

3 (2.1)

4 (2.6)

0.53

Fibre and Macronutrients

      

   Total Energy (MJ/d)

8 (2.1)

8 (1.8)

0.85

8 (2.1)

8 (2.0)

0.51

   Carbohydrate (g/d)

235 (68.2)

250 (58.5)

0.25

238 (68.6)

236 (60.9)

0.87

   Protein (g/d)

70 (15.1)

68 (14.8)

0.48

70 (15.4)

72 (13.6)

0.29

   NSP (g/d)

14 (5.0)

16 (7.4)

0.15

14 (5.8)

15 (4.1)

0.53

   Calcium (mg/d)

779 (235.9)

821 (220.5)

0.37

787 (239.8)

783 (212.7)

0.92

  1. ‡P values determined by ANOVA. Results presented as [mean (± SD)]. PUFA: polyunsaturated fatty acid. MUFA: monounsaturated fatty acid. SFA: saturated fatty acid. NSP: non-starch polysaccharide. For one case for which mutational status had been determined no dietary data was available. Therefore, for all testing with dietary factors the number of combined cases in the wildtype and mutated groups available for analysis was 185.
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BMC Cancer

ISSN: 1471-2407

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