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Table 4 Comparison between beclin 1 mRNA and protein expression in breast cancer

From: Genetic and epigenetic silencing of the beclin 1gene in sporadic breast tumors

Beclin 1 mRNA expression

Beclin 1 protein expression (IHC)

(Quantitative RT-PCR)

Positive

Negative

Positive (6)

6

0

Negative (14)

1

13

 

p < 0.001

 
  1. Positive means that the expression level of beclin 1 mRNA/protein in breast tumors increased compared with the corresponding adjacent normal tissues. And negative means that the expression level of beclin 1 mRNA/protein in breast tumors decreased compared with the corresponding adjacent normal tissues. The association between beclin 1 mRNA and protein expression was analyzed using the χ2 test.