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Table 4 Multiple Cox regression analysis of VEGFR1 adjusting for T stage, N stage, vascular invasion as well as post-operative adjuvant therapy

From: Role of the VEGF ligand to receptor ratio in the progression of mismatch repair-proficient colorectal cancer

Feature   HR (95%CI) P-value HR (95%CI) P-value
VEGFR1 Baseline 1.0 0.024 1.0 0.032
  1-unit increase 1.009 (1.001-1.017)   1.009 (1.001-1.017)  
pT stage pT1-2 1.0 <0.001 1.0 <0.001
  pT3-4 5.67 (2.03-15.8)   5.79 (2.07-16.19)  
pN stage pN0 1.0 <0.001 1.0 <0.001
  pN1-2 4.81 (2.53-9.16)   5.1 (2.61-9.97)  
Vascular invasion Absent 1.0 <0.001 1.0 <0.001
  Present 2.82 (2.82-4.75)   2.93 (1.71-5.02)  
Post-operative therapy None    1.0 0.562
  Treated    0.85 (0.49-1.48)