Effects of WX-UK1 (SPI), Celecoxib
® (COXI), and Galardin
® (MMPI) on the sprouting capacity of HUVEC spheroids in collagen gel. Shown are the mean numbers of sprouts of HUVEC with standard deviation from 15-20 individual spheroids performed in three independent experiments. HUVEC were incubated with conditioned supernatants of FaDu (A) and HeLa cells (B). Lower panels show representative images of HUVEC spheroids.