Favourable ten-year overall survival in a Caucasian population with high probability of hereditary breast cancer

BMC Cancer

Table 1 Clinicopathological characteristics of patients according to familial risk group

Family Risk Group
	No family history		Intermediate-Slightly increased risk		High Risk		p
	(n = 4912)		(n = 691)		(n = 320)
Characterics	N°	%	N°	%	N°	%
Histotype
Ductal	3936	80.1	565	81.8	251	78.4	NS
Lobular	606	12.3	83	12.0	44	13.7	NS
Tubular	93	1.9	13	1.9	2	0.6	NS
Colloid	64	1.3	10	1.4	0	0	NS
Medullary	26	0.5	6	0.9	13	4.1	< .0001
Other	187	3.9	14	2.0	10	3.2	NS
Stage
I	2322	47.3	312	45.1	141	44.1	NS
II	1546	31.5	255	36.9	127	39.7	< .0001
III	802	16.4	112	16.2	48	15.0	NS
IV	216	4.4	11	1.8	1	0.3	<.0001
X	23	0.5	1	0.1	3	0.9	NS
ER
Positive	3286	66.8	448	64.8	147	45.9	< .0001
Negative	757	15.4	139	20.2	149	46.6	< .0001
Unknown	869	17.8	103	15.0	24	7.5	< .0001
PgR
Positive	2796	56.9	408	59.1	135	42.2	< .0001
Negative	1109	22.5	173	25.0	162	50.6	< .0001
Unknown	1007	20.6	110	15.9	23	7.2	< .0001
Ki67
Low (0-19)	2523	51.4	383	55.4	185	57.8	NS
High (20-100) 1109		22.5	167	24.2	103	32.2	NS
Unknown	1007	20.6	141	20.4	32	10.0	NS
Chemotherapy
Yes	1851	37.7	350	50.7	106	33.1	< .0001
No	3061	62.3	341	49.3	214	66.9	< .0001
Hormone therapy
Yes	2804	57.1	380	55.0	106	33.1	< .0001
No	2108	42.9	311	45.0	214	66.9	< .0001

ISSN: 1471-2407