BMC Cancer

Table 2 Major omega 6 and omega 3 fatty acids in tissues of mice.

From: Maternal consumption of canola oil suppressed mammary gland tumorigenesis in C3(1) TAg mice offspring

Liver 21 days
Fatty acid	Corn oil diet	Canola diet	p value
18:2 LA	17.35 ± 1.22	12.10 ± 0.90	<0.0001*
18:1+18:3 ALA	9.59 ± 2.16	20.29 ± 2.04	<0.0001*
20:4 AA	18.40 ± 1.60	10.08 ± 0.57	<0.0001*
20:5 EPA	0.09 ± 0.02	1.39 ± 0.20	<0.0001*
22:6 DHA	5.04 ± 0.81	11.22 ± 0.46	<0.0001*
22:5 DPA	0.64 ± 0.08	0.53 ± 0.06	0.023*
Liver 130 days
18:2 LA	23.96 ± 2.74	22.91 ± 0.93	0.5565
18:1+18:3 ALA	18.19 ± 2.47	24.14 ± 1.01	0.0289*
20:4 AA	13.82 ± 0.46	10.33 ± 0.49	0.0041*
20:5 EPA	0.045 ± 0.04	0.10 ± 0.04	0.2382
22:6 DHA	5.37 ± 0.49	3.83 ± 0.17	0.0127*
22:5 DPA	0.315 ± 0.04	0.24 ± 0.03	0.0817
Mammary gland 21 days
18:2 LA	26.25 ± 1.32	6.74 ± 1.99	0.0000*
18:1+18:3 ALA	29.26 ± 0.70	50.99 ± 1.98	0.0000*
20:4 AA	0.67 ± 0.12	0.31 ± 0.11	0.0043*
20:5 EPA	0.06 ± 0.01	0.08 ± 0.05	0.4050
22:6 DHA	0.08 ± 0.02	0.02 ± 0.01	0.0008*
22:5 DPA	0.01 ± 0.01	0.06 ± 0.03	0.0124*
Mammary gland 130 days
18:2 LA	37.15 ± 0.78	35.77 ± 2.30	0.2879
18:1+18:3 ALA	0.40 ± 0.01	0.38 ± 0.03	0.1996
20:4 AA	0.13 ± 0.01	0.11 ± 0.03	0.3218
20:5 EPA	0.02 ± 0.01	0.00 ± 0.00	0.0000*
22:6 DHA	0.01 ± 0.00	0.01 ± 0.01	0.2415
22:5 DPA	0.02 ± 0.00	0.00 ± 0.00	0.0000*

*values in row are significantly different by T-test
The percents of assayed fatty acids of liver and mammary gland at 21 and 130 days old are shown. The results of T-tests between each pair of treatments for each tissue and time-point are shown, n = 3 to 5 mice per diet per time point. A p < 0.05 is taken to be statistically significant and is further indicated by an *

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