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Table 1 Relationship between morphological features, kinetic patterns of enhancement and clinicopathological characteristics of patients

From: Relationship between morphological features and kinetic patterns of enhancement of the dynamic breast magnetic resonance imaging and clinico-pathological and biological factors in invasive breast cancer

   Morphological features Kinetic features
   Margin Enhancement internal   Peak of maximum enhancement % of maximun enhancement < 2' Curve Type
Characteristics N°* A B Hom Het/Rim   < 2' ≥ 2' ≤ 150% > 150% I II III
Total cases 64      68        
Menopausal status              
Premenopausal 26 4 (15.4) 22 (84.6) 4 (15.4) 22 (84.6) 29 5 (17.2) 24 (82.8) 14 (48.3) 15 (51.7) 2 (6.9) 11 (37.9) 16 (55.2)
Postmenopausal 38 12 (31.6) 26 (68.4) 8 (21.1) 30 (78.9) 39 12 (30.8) 27 (69.2) 25 (64.1) 14 (35.9) 3 (7.7) 13 (33.3) 23 (59)
Tumor size    p = 0.015         
T1 (<2 cm) 42 14 (33.3) 28 (66.7) 12 (28.6) 30 (71.4) 43 10 (23.2) 33 (76.8) 28 (65.1) 15 (34.9) 4 (9.3) 13 (30.2) 26 (60.5)
≥ T2 (≥ 2 cm) 22 2 (9.1) 20 (90.9) 0 22 (100) 25 7 (28) 18 (72) 11 (44) 14 (56) 1 (4) 11 (44) 13 (52)
Nodal status              
N (-) 35 9 (25.7) 26 (74.3) 7 (20) 28 (80) 35 10 (28.6) 25 (71.4) 20 (57.1) 15 (42.9) 3 (8.6) 10 (28.6) 22 (62.8)
N (+) 29 8 (27.6) 21 (72.4) 6 (20.7) 23 (79.3) 33 8 (24.2) 25 (75.8) 19 (57.6) 14 (42.4) 2 (6.1) 15 (45.4) 16 (48.5)
Histological grade              
I 22 6 (27.3) 16 (72.7) 5 (22.7) 17 (77.3) 24 4 (16.7) 20 (83.3) 14 (58.3) 10 (41.7) 4 (16.6) 10 (41.7) 10 (41.7)
II 24 6 (25) 18 (75) 5 (20.8) 19 (79.2) 26 7 (26.9) 19 (73.1) 13 (50) 13 (50) 1 (3.8) 8 (30.8) 17 (65.4)
III 18 4 (22.2) 14 (77.8) 2 (11.1) 16 (88.9) 18 6 (33.3) 12 (66.7) 12 (66.7) 6 (33.3) 0 6 (33.3) 12 (66.7)
Vascular invasion         p = 0.016    
Yes 27 8 (29.6) 19 (70.4) 4 (14.8) 23 (85.2) 29 6 (20.7) 23 (79.3) 22 (75.9) 7 (24.1) 2 (6.9) 11 (37.9) 16 (55.2)
No 37 8 (21.6) 29 (78.4) 8 (21.6) 29 (78.4) 39 11 (28.2) 28 (71.8) 17 (43.6) 22 (56.4) 3 (7.7) 13 (33.3) 23 (59)
Mitotic Index       p = 0.036 p = 0.03    
≤ 5 29 6 (20.7) 23 (79.3) 5 (17.2) 24 (82.8) 33 4 (12.1) 29 (87.9) 14 (42.4) 19 (57.6) 4 (12.1) 13 (39.4) 16 (48.5)
>5 35 10 (28.6) 25 (71.4) 7 (20) 28 (80) 35 13 (37.1) 22 (62.9) 25 (71.4) 10 (28.6) 1 (2.9) 11 (31.4) 23 (65.7)
Peritumor inflammation           p = 0.042
Yes 36 10 (27.8) 26 (72.2) 7 (19.4) 29 (80.6) 37 11 (29.7) 26 (70.3) 23 (62.2) 14 (37.8) 1 (2.7) 10 (27) 26 (70.3)
No 28 6 (21.4) 22 (78.6) 5 (17.9) 23 (82.1) 31 6 (19.4) 25 (80.6) 16 (51.6) 15 (48.4) 4 (12.9) 14 (45.2) 13 (41.9)
  1. * Four cases showed a non-nodular enhancement, so the morphological features were analyzed in only 64 cases, and the kinetic features in all 68 cases. Data are expressed as number of cases (percentage).
  2. Abbreviations: A, well-defined (regular); B, ill-defined (irregular or spiculated); Hom: homogeneous; Het: heterogeneous.