Table 3 Relation of HAX1 expression to breast cancer prognostic factors

median of relative over-

expression (lower and

upper quartile values)

median of relative over-

expression (lower and

upper quartile values)

Size (cm)

< 2

5

0.82 (0.35-1.30)

0.82 (0.41-2.04)

> 2

10

2.2 (1.38-4.15)*

2.99 (1.70-7.5)*

Nodal status

Positive

9

1.3 (1.54-4.15)

1.7 (0.82-2.90)

Negative

6

2.35 (0.82-2.18)

4.05 (2.04-7.75)*

Histology

Ductal

7

1.3 (0.36-2.23)

2.04 (0.41-3.34)

Lobular

3

1.38 (1.33-2.83)

2.62 (1.54-5.50)

Papillary

4

3.77 (2.03-7.10)

6.81 (1.87-14.46)

Mixed

1

1.08

1.7

Grade

1

3

1.3 (0.36-1.54)

2.04 (0.41-2.89)

2

9

1.88 (1.08-2.83)

2.62 (1.09-5.48)

3

2

3.17 (2.18-4.15)

5.2 (2.65-7.75)

ER status

Positive

9

1.33 (1.08-1.54)

2.04 (1.55-2.89)

Negative

6

2.51 (1.88-4.15)

4.06 (1.09-7.75)

PR status

Positive

8

1.32 (0.95-1.46)

1.9 (1.18-2.76)

Negative

7

2.23 (1.88-4.15)

3.34 (1.09-7.75)*

HER2 status

Positive

7

1.30 (0.82-1.54)

1.7 (0.82-2.89)

Negative

8

2.51 (1.63-4.75)

4.06 (1.86-9.36)*