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Figure 2 | BMC Cancer

Figure 2

From: iASPP is over-expressed in human non-small cell lung cancer and regulates the proliferation of lung cancer cells through a p53 associated pathway

Figure 2

Down-regulation of iASPP inhibits proliferation of lung cancer cells. (A) Pictures for Lentivirus tranfection of blank control (CON), nonsense shRNA (NC) and iASPP shRNA (KD). (B) The iASPP mRNA level was downregulated by iASPP shRNA in A549, 95D and H1299 cells. (C) The iASPP protein level was downregulated by iASPP shRNA in A549, 95D and H1299 cells. (D-E) Proliferation of A549 cells (D) and 95D cells (E) were inhibited when treated with iASPP shRNA by MTT assay. (F-G) Proliferation of A549 cells (F) and 95D cells (G) were inhibited when treated with iASPP shRNA by BrdU assay. CON: blank control; NC, nonsense shRNA; KD: iASPP shRNA. Results represent the mean ± S.D. of three independent experiments.

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BMC Cancer

ISSN: 1471-2407

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