| Plasma concentration, μM |  | |||
---|---|---|---|---|---|
Amino acid | Patients (n = 141) | Controls (n = 423) | pvalue | ||
 | Mean | SD | Mean | SD |  |
Thr | 115.6 | 28.6 | 115.9 | 25.4 | 0.92 |
Ser | 117.1 | 19.9 | 111.4 | 17.9 | 0.003 |
Asn | 45.1 | 8.2 | 44.8 | 7.2 | 0.72 |
Glu | 46.7 | 19.4 | 45.7 | 19.5 | 0.60 |
Gln | 580.5 | 93.3 | 587.9 | 83.5 | 0.40 |
Pro | 168.0 | 43.6 | 150.9 | 41.4 | < 0.001 |
Gly | 263.6 | 63.2 | 237.0 | 57.3 | 0.000 |
Ala | 422.3 | 97.4 | 383.7 | 88.9 | 0.000 |
Cit | 34.4 | 10.6 | 33.2 | 8.3 | 0.20 |
ABA | 24.2 | 8.4 | 23.2 | 6.9 | 0.20 |
Val | 244.8 | 47.5 | 239.8 | 46.1 | 0.28 |
Met | 29.4 | 6.1 | 28.0 | 5.2 | 0.013 |
Ile | 84.3 | 22.1 | 69.7 | 17.5 | < 0.001 |
Leu | 131.8 | 34.3 | 122.4 | 27.6 | 0.003 |
Tyr | 80.7 | 15.6 | 75.8 | 15.5 | 0.001 |
Phe | 67.9 | 12.2 | 63.9 | 11.2 | 0.001 |
His | 77.3 | 15.0 | 80.8 | 10.7 | 0.010 |
Trp | 59.3 | 12.0 | 59.8 | 10.9 | 0.67 |
Orn | 67.6 | 19.7 | 54.4 | 12.3 | < 0.001 |
Lys | 211.5 | 36.2 | 200.3 | 34.1 | 0.001 |
Arg | 101.3 | 21.6 | 98.1 | 17.8 | 0.12 |