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Table 4 Analysis of overall survival from diagnosis of carcinomatosis to last follow-up in 167 patients with peritoneal carcinomatosis of colonic origin

From: Evaluation of Best Supportive Care and Systemic Chemotherapy as Treatment Stratified according to the retrospective Peritoneal Surface Disease Severity Score (PSDSS) for Peritoneal Carcinomatosis of Colorectal Origin

Characteristics n Median Survival (Months) P (Univariate) P (Multivariate)
RR [CI]
Sex    0.45  
   Male 93 8   
   Female 74 8   
Age (Years)    0.58  
   < 60 85 8   
   ≥ 60 82 8   
Disease Presentation    0.45  
   Synchronous 52 7   
   Metachronous 115 8   
Location    0.07  
   Colon 123 8   
   Rectum 44 7   
Site of Metastases    0.15  
   Peritoneum Only 64 7   
   Peritoneum+Lung/Liver 67 8   
   Peritoneum+Other 36 9   
Systemic Chemotherapy    0.003  
   None 83 5   
   5FU/L 42 11   
   Modern 42 12   
Clinical Symptoms    < 0.001  
   Asymptomatic 55 18   
   Mild 78 6   
   Severe 34 3   
Extent of Carcinomatosis    0.002  
   PCI < 10 103 6   
   PCI 10 to 20 47 11   
   PCI > 20 17 4   
Histopathology    0.003  
   Well Differentiated 19 7   
   Moderately Differentiated 89 11   
   Poorly Differentiated/Signet 59 6   
PSDSS Stage    0.003 0.001
   Stage I 6 39   2.1 [1.3 - 4.9]
   Stage II 53 19   
   Stage III 33 7   
   Stage IV 75 4   
PSDSS Stage    < 0.001 < 0.001
   Stage I/II 59 22   2.8 [1.5 - 5.4]
   Stage III/IV 108 5