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Table 1 Classification of drug interactions by Drug Interaction Facts Software 13

From: Potential drug interactions and duplicate prescriptions among ambulatory cancer patients: a prevalence study using an advanced screening method

Classification Description
Severity  
1 Major: life-threatening or permanent damage
2 Moderate: deterioration of patient's status, treatment is required
3 Minor: bothersome or little effect
Documentation  
1 Established: proven to occur in well-controlled studies
2 Probable: very likely, but not proven clinically
3 Suspected: may occur; some good data, but needs more study
4 Possible: could occur, but data are very limited
5 Unlikely: doubtful; no good evidence of a clinical effect